WebCentral pontine myelinolysis Videos, Flashcards, High Yield Notes, & Practice Questions. Learn and reinforce your understanding of Central pontine myelinolysis. - Osmosis is … Central pontine myelinolysis is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons (an area of the brainstem). It is predominately iatrogenic (treatment-induced), and is characterized by acute paralysis, dysphagia (difficulty swallowing), dysarthria (difficulty speaking), … See more Symptoms depend on the regions of the brain involved. Prior to its onset, patients may present with the neurological signs and symptoms of hyponatraemic encephalopathy such as nausea and vomiting, … See more The currently accepted theory states that the brain cells adjust their osmolarities by changing levels of certain osmolytes like inositol, betaine, and glutamine in response to varying serum osmolality. In the context of chronic low plasma sodium (hyponatremia), the … See more To minimise the risk of this condition developing from its most common cause, overly rapid reversal of hyponatremia, the hyponatremia should be corrected at a rate not exceeding … See more • MedPix Images of Osmotic Myelinolysis See more The most common cause is overly-rapid correction of low blood sodium levels (hyponatremia). Apart from rapid correction of hyponatraemia, there are case reports of central pontine … See more It can be diagnosed clinically in the appropriate context, but may be difficult to confirm radiologically using conventional imaging … See more Though traditionally the prognosis is considered poor, a good functional recovery is possible. All patients at risk of developing … See more
Central Pontine Myelinolysis - Overview - Brain and Life
WebNov 26, 2016 · Central pontine myelinolysis (CPM) is an acute demyelinating neurological disorder affecting primarily the central pons and is frequently associated with rapid correction of hyponatremia. Common clinical manifestations of CPM include spastic quadriparesis, dysarthria, pseudobulbar palsy, and encephalopathy of various degrees; … WebCentral pontine myelinolysis, a subset of ODS, was first described in 1959 (coinciding with the introduction of plastic tubing and widespread use of IV fluid therapy) by Adams and Victor. ODS has been cited to account for 0.06% of all admissions to the med - ical service of a general hospital.1 A large autopsy series found a giggleberry fair new hope pa
Gd-DTPA Enhancement in MR Imaging of Central Pontine Myelinolysis ...
WebOne of the well recognized stimuli for central pontine myelinosis (CPM) is the rapid correction of chronic hyponatraemia. Conventionally this has been perceived to lead to … WebFeb 23, 2024 · Central pontine myelinolysis is a demyelinating disorder that affects the brainstem white matter, mostly central pons and occasionally cerebral hemispheres (then … WebCentral pontine myelinolysis; Other names: Osmotic demyelination syndrome, central pontine demyelination: Axial fat-saturated T2-weighted image showing hyperintensity in … ftc stick with security