WebBackground . The TARDIS trial assessed the safety and efficacy of intensive versus guideline antiplatelet agents given for one month in patients with acute stroke or TIA. The aim of this substudy was to assess the effect of antiplatelet agents taken at baseline on platelet function reactivity and activation. Methods . Platelet function, assessed by … WebBath PM et al. Statistical analysis plan for the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial. Int J Stroke 2015. 10:449-51. Bath PM et al. …
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WebThe Triple Antiplatelets for Reducing Dependency in Ischemic Stroke (TARDIS) trial is an international, prospective, randomized open-label blinded end point-controlled trial … WebWithin the TARDIS trial, intensive antiplatelet therapy resulted in more bleeding and bleeding of greater severity (OR 2 · 54, 95% CI 2.05–3.16) . The POINT trial found that hemorrhage occurred in 0.9% of patients receiving DAPT (clopidogrel plus aspirin) but only in 0.4% of patients receiving aspirin alone (HR 2.32; 95% CI, 1.10–4.87) [ 16 ]. rocketrx.com
Scientific summary - Triple versus guideline antiplatelet therapy to ...
WebMar 14, 2024 · The trial population had a mean age of 69 and was 63 percent male. Only 11 percent had a prior stroke and 19 percent had diabetes. The index event was an ischemic stroke for 70 percent of participants and TIA for 30 percent. A total of 3,096 patients were randomized before the trial was halted. The original target enrollment was 4,100 patients. WebFeb 24, 2024 · The TARDIS trial was therefore conducted. It randomly assigned patients within 48 hours of a noncardioembolic ischemic stroke or TIA to intensive antiplatelet … WebMay 18, 2016 · TARDIS Trial Investigators Safety and efficacy of intensive vs. guideline antiplatelet therapy in high-risk patients with recent ischemic stroke or transient ischemic attack: rationale and design of the Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) trial (ISRCTN47823388). o the deep deep love of jesus trinity hymnal