WebPDB Description: nmr and restrained molecular dynamics study of the three-dimensional solution structure of toxin fs2, a specific blocker of the l-type calcium channel, isolated from black mamba venom. PDB Compounds: (A:) toxin fs2. … WebJun 23, 1998 · The predicted Ca2+ channel binding site also occurs in closely related toxins, C10S2C2 and S4C8. Therefore, it is likely that these toxins also will block L-type Ca2+ channels. To test the proposed binding site on calciseptine and FS2, an eight-residue peptide, named L-calchin (L-type calcium channel inhibitor), was synthesized and …
T 2 Toxin - an overview ScienceDirect Topics
WebAlbrand, J.P. et al., NMR and restrained molecular dynamics study of the three-dimensional solution structure of toxin FS2, a specific blocker of the L-type calcium channel, isolated from black mamba venom. Biochemistry (1995) Release Date 1995-03-31 Peptides TOXIN FS2: A SMTL:PDB. WebA conjugate of the ligand of FS2 venom dihydropyridine receptors with a cationic arginine-containing oligopeptide was synthesized. It was found that the conjugate provides siRNA delivery to murine myotubes differentiated in vitro. mark hoffmann imperial mo
UniProt
WebMay 1, 1992 · NMR and Restrained Molecular Dynamics Study of the Three-Dimensional Solution Structure of Toxin FS2, a Specific Blocker of the L-Type Calcium Channel, … WebThe three-dimensional solution structure of toxin FS2, a 60-residue polypeptide isolated from the venom of black mamba snake (Dendroaspis polylepis polylepis), has been … WebSep 1, 2002 · Comparative molecular modelling study of the calcium channel blockers nifedipine and black mamba toxin FS2. Schleifer, KJ. Evaluation of the role of proline residues flanking the RGD motif of dendroaspin, an inhibitor of platelet aggregation and cell adhesion. Lu, X; Sun, Y; Shang, D. mark hoffman md prohealth